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Trimeric and Tetrameric A‑Type Procyanidins from Peanut Skins

AbstractPeanut skins are a rich source of oligomeric and polymeric procyanidins. The oligomeric fractions are dominated by dimers, trimers, and tetramers. A multistep chromatographic fractionation led to the isolation of four new A-type procyanidins of tri- and tetrameric structures. The structures of the new trimers were defined by NMR, electronic circular dichroism, and MS data as epicatechin-( READ MORE

Influence of Degree-of-Polymerization and Linkage on the Quantification of Proanthocyanidins using 4‑Dimethylaminocinnamaldehyde (DMAC) Assay

AbstractProanthocyanidins (PACs) are naturally occurring flavonoids possessing health beneficial bioactivities. Their quantification often utilizes the 4-dimethylaminocinnamaldehyde (DMAC) spectrophotometric assay with the assumption that molar absorption coefficients (MACs) are similar across the various PAC species. To assess the validity of this assumption, individual PAC monomers and oligom READ MORE

Reactivation of latent HIV-1 by new semi-synthetic ingenol esters

AbstractThe ability of HIV to establish long-lived latent infection is mainly due to transcriptional silencing of viral genome in resting memory T lymphocytes. Here, we show that new semi-synthetic ingenol esters reactivate latent HIV reservoirs. Amongst the tested compounds, 3-caproyl-ingenol (ING B) was more potent in reactivating latent HIV than known activators such as SAHA, ingenol 3,20-diben READ MORE

Welcome To Site

Welcome to Planta Analytica LLC, a leading provider in high performance separation services and compound isolation. We offer a range services for the dietary, supplemental, pharmaceutical and agrochemical markets, including and not limited to process development, impurity isolation, and large scale purifications for biological assays. Make sure to browse through our catalogue of high purity reference standards and read up on some of our recent publications and press releases.

Welcome To Site

Welcome to Planta Analytica LLC, a leading provider in high performance separation services and compound isolation. We offer a range services for the dietary, supplemental, pharmaceutical and agrochemical markets, including and not limited to process development, impurity isolation, and large scale purifications for biological assays. Make sure to browse through our catalogue of high purity reference standards and read up on some of our recent publications and press releases.

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