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Influence of Degree-of-Polymerization and Linkage on the Quantification of Proanthocyanidins using 4‑Dimethylaminocinnamaldehyde (DMAC) Assay

AbstractProanthocyanidins (PACs) are naturally occurring flavonoids possessing health beneficial bioactivities. Their quantification often utilizes the 4-dimethylaminocinnamaldehyde (DMAC) spectrophotometric assay with the assumption that molar absorption coefficients (MACs) are similar across the various PAC species. To assess the validity of this assumption, individual PAC monomers and oligom READ MORE

Reactivation of latent HIV-1 by new semi-synthetic ingenol esters

AbstractThe ability of HIV to establish long-lived latent infection is mainly due to transcriptional silencing of viral genome in resting memory T lymphocytes. Here, we show that new semi-synthetic ingenol esters reactivate latent HIV reservoirs. Amongst the tested compounds, 3-caproyl-ingenol (ING B) was more potent in reactivating latent HIV than known activators such as SAHA, ingenol 3,20-diben READ MORE

Characterization of Primary Standards for Use in the HPLC Analysis of the Procyanidin Content of Cocoa and Chocolate Containing Products [FREE DOWNLOAD]

AbstractThis report describes the characterization of a series of commercially available procyanidin standards ranging from dimers DP = 2 to decamers DP = 10 for the determination of procyanidins from cocoa and chocolate. Using a combination of HPLC with fluorescence detection and MALDI-TOF mass spectrometry, the purity of each standard was determined and these data were used to determine relative READ MORE

Welcome To Site

Welcome to Planta Analytica LLC, a leading provider in high performance separation services and compound isolation. We offer a range services for the dietary, supplemental, pharmaceutical and agrochemical markets, including and not limited to process development, impurity isolation, and large scale purifications for biological assays. Make sure to browse through our catalogue of high purity reference standards and read up on some of our recent publications and press releases.

Welcome To Site

Welcome to Planta Analytica LLC, a leading provider in high performance separation services and compound isolation. We offer a range services for the dietary, supplemental, pharmaceutical and agrochemical markets, including and not limited to process development, impurity isolation, and large scale purifications for biological assays. Make sure to browse through our catalogue of high purity reference standards and read up on some of our recent publications and press releases.

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